AMNIOMTM INJECTABLE MULTI-POTENTIAL TISSUE MATRIX. 0.25ML

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AMNIOMTM INJECTABLE MULTI-POTENTIAL TISSUE MATRIX. 0.25ML
Item Number: AG-010025
Price:
$545.00

AMNIOMTM INJECTABLE MULTI-POTENTIAL TISSUE MATRIX. 0.25ML

AmnioMTM Injectable Multi-Potential Tissue Matrix. 0.25ml

Engineered by Nature to Potentiate Wound Healing and Bone Regeneration AmnioMTM™ is a novel, multipotential extracellular matrix (ECM) which acts as a natural scaffold for cellular attachment. While providing structural support to cells, AmnioMTM™ assists in regulating cell adhesion, cell division, and cell migration.

 

Introducing AmnioMTM, a cryopreserved amnion allograft, derived from the placenta of live, healthy donors.  The human placenta, besides playing a critical and

fundamental role in fetal development, nutrition and protection, represents a significant source of multipotent stem cells and fetal healing

components.  AmnioMTM provides a three dimensional extracellular matrix, which acts as a natural scaffold for cellular attachment in the body.

AmnioMTM also contains multipotential cells that are capable of differentiating into all three germ layers of the human body. The ECM houses and

provides structural support to cells while regulating cell adhesion, cell division, cell differentiation, and cell migration. Together in this complex, dynamic

bone and wound healing system, AmnioMTM delivers osteogenic, osteoconductive and osteoinductive  elements to enhance and proliferate wound and

bone healing and repair Amniotic allografts have been scientifically documented and clinically proven to be efficacious in a wide array of surgical applications

ranging from: anti-adhesion, anti-inflammatory barrier in spinal laminectomies,ocular surface ophthalmic procedures, and diabetic wound care management.


Potential Applications:

Wound Covering

Ridge Augmentation

Soft Tissue Repair

Periodontal Defects

Boney Defects

TMJ

Multipotent Cells Identified to be Present within Amniotic Membrane Tissue:

Amniotic Epithelial Cells

Amniotic Mesenchymal Cells

Growth Factors Identified to be Present within Amniotic Membrane Tissue: EGF, TGF-β, FGF, PDGF A & B, VEGF, IGF 1 & 2

Bio-Active Design AmnioMTM™ retains the natural composition of extracellular matrix molecules including collagen, structural proteins, growth factors, glycoproteins, and glycosaminoglycans.

Presence of multipotent cells may have bi-potential osteogenic and adipogenic differentiation capabilities.

AmnioMTM™ has anti-inflammatory, anti-microbial, anti-bacterial, and anti-adhesive as well as immunoprivileged properties.

CHORION FREE

 

  Immune privileged; Class II anti-gens not expressed, reducing the risk of immunological rejection.
β-defensins, anti-microbial peptides, inhibit bacterial infections.
            Multipotential cells capable of differentiating, providing ancillary healing benefits.
            The extracellular matrix creates a native scaffold for supporting wound and bone healing.
    Derived from live, healthy donors.


A Dynamic Bone and Wound Healing System


        Component:
Amniotic Morselized Tissue
Feature:
Has been shown to be immune privileged (Class II antigens rarely expressed) anti-microbial, anti-bacterial.
Benefit:
Donor source from live healthy patients resulting in less complications and donor rejection versus traditional allografts, xeno-
 grafts. And compared to autografts, there is no need for a second surgical procedure to harvest bone resulting in less site morbidity, pain
  and associated costs.
 
Component:
Three Dimensional Extracellular Matrix Scaffold
         Feature:
          Provides mechanical properties such as collagen I-VI and elastin creating osteoconductive environment for cell attachment and     hosting.
            Benefit:
            Provides structural matrix for use in filling soft tissue defects and bone voids.

          Component:
          Fibronectin, Laminins, Vitronectin and Cytokines.
          Feature:
          Proteins from the ECM that signal cells to attach and migrate. Serve as adhesion ligands and allows for intercellular communication.
          Benefit:
            Rarely evokes an immune response with patients experiencing less pain, swelling and inflammation.
 
         Component:
          Epidermal Growth Factor (EGF), Transforming Growth Factor (TGF- β Fibroblast Growth Factor (FGF),
          Platelet Derived Growth Factor A&B ( PDGF A&B)
          Feature:
          EGF proliferates epithelial cells. TGF-β acts as an anti-inflammatory, reduces scar tissue, speeding up healing. FGF proliferates cells for
          collagen matrix. PDGF A&B proliferates connective tissue and enhances soft tissue
         Benefit:
         Has been shown to accelerate wound healing rates, bone formation and soft tissue attachment. Also healthcare economics
         are positive when comparing AmnioMTM to other osteoinductive and osteogenic materials or synthetic products.
 
         Component:
         Hyaluronic Acid
         Feature:
             It’s been reported to increase osteoblastic bone formation in vitro through increased mesenchymal cell
          differentiation and cell migration.
          Benefit:
          Has the potential to reduce scar formation and improve vascularity, resulting in better tissue formation.


Product Characteristics FDA-registered product regulated under 21 CFR Part 1271 and Section 361 of the Public Health Service Act. Cryopreserved liquid allograft, derived from live birth tissue and cells, which is not dependent on the metabolic activity of living cells. Extensive donor selection and screening, according to AATB guidelines, is performed to ensure clinical safety. For homologous use only. *******PLEASE CALL FOR SHIPPING DETAILS. PRODUCT IS ORDERED PER CASE, OR A CRYO FREEZER CAN BE MADE AVAILABLE. SHIPPED IN CRYO PRESERVED PACKAGE, WITH 4 DAY SHIP WINDOW. - CALL FOR FURTHER DETAILS

 

Case Studies

Lateral Ridge Augmentation Using AmnioMTM™

Case Report Soft Tissue Grafting Using AmnioMTM™ to Treat Gingival Recession

Soft Tissue Grafting Using Acellular Dermal Matrix with AmnioMTM™

Use of AmnioMTM™in Guided Tissue Regeneration in Severe Periodontitis

Alveolar Fenestration Repair and Simultaneous Sinus Augmentation Using AmnioMTM™

 

Please follow the links for Clinical material on the use of Amnion based material in Medicine

Available PDF Articles

Basic Science

Properties of the Amniotic Membrane for Potential Use in Tissue Engineering

 

How do Mesenchymal Stem Cells Repair

 

Amniotic Fluid and Placental Stem Cells

 

Human Amnion Tissue as an Antiadhesion AntiInflammatory Barrier in an Ovine Laminectomy Model

 

Not Just Fetal Urine Anymore

 

Scarless Skin Wound Repair in the Fetus

 

Term Amniotic Membrane is a High throughout Source for Multipotent Mesenchymal Stem Cells

 

Inducing of Angiogenesis is the net effect of the Amniotic Membrane without Epithelial Cells

 

Scarless Fetal Healing

 

Amniotic Healing in Dental 

A Prospective Pilot Study on the Clinical Application of Stromal Vascular Fraction Stem Cells in Treatment Gingival Recession Defects

 

Histological and Computed Tomography Analysis of Amnion Chorion Membrane in Guided Bone Regeneration in Socket Augmentation

 

Cryopreserved Amniotic Membrane for Modulation of Periodontal Soft Tissue Healing

 

Wound Healing

Amniotic Membrane as a Biological Dressing in the Management of Burns

 

Human Amnion as an Adjunct in Wound Healing

 

Human Amniotic Membrane A Versatile Wound Dressing

 

In Vitro Angiogenesis on the Human Amniotic Membrane

 

A Comparative Histopathological Investigation of the Effect of Lyophilized Amniotic Membrane on Wound Healing

 

Amniotic Membrane Allograft for Treatment in Diabetic Wound Care Management

 

Amniotic Membrane Dressing Versus Conventional Dressing in Lower Limb Varicose Ulcer

 

Bone Healing

Effect of Human Amniotic Fluid on Fracture Healing in Rat Tibia

 

Effect of Human Amniotic Fluid on Bone Healing

 

Efficacy of a Novel Cell Based Therapy on Bone Healing in a Critical Sized Rat Femur Defect

 

Amniotic Healing in Medicine

Isolation of Amniotic Stem Cell Lines with Potential for Therapy  

 

Surface Amniotic Membrane Transplantation has Many Advantages

 

Immunogenicity of Human Amnion Epethial Cells After Transplantation into Volunteers

 

Implantation of Amniotic Membrane to Reduce Postlaminectomy of Epidural Adhesions

 

Use of Amniotic Membrane Transplantation in the Treatment of Venous Leg Ulcers

 

Versatile Biomaterial Suitable for Treaty Acute Ocular Traumatic Injuries

Product Reviews

Works !
We have been having very good success and are starting to use it more often. It has made the recovery for our patients so much more pleasant.
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