NG-1 NANOGEN Nanocrystaline Calcium Sulfate Grafting Material, 2 gram kit

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NG-1 NANOGEN Nanocrystaline Calcium Sulfate Grafting Material, 2 gram kit
Item Number: NG-1

NG-1 NANOGEN Nanocrystaline Calcium Sulfate Grafting Material, 2 gram kit

NG-1 NANOGEN Nanocrystaline Calcium Sulfate Grafting Material, 2 gram kit


Histological evidence of bone formation in small defect grafted with NanoGen.

NanoGen is a proprietary product developed by Orthogen, LLC. Microcrystalline calcium sulfate is converted to grains of calcium sulfate (size range 200 to 900 nanometers), which are tightly compressed together to form granules in sizes ranging from 400 to 1000 microns. This unique microscopic structure imparts unique properties to the product. NanoGen undergoes controlled degradation over a period of 12 weeks as compared to 4 to 6 weeks for traditional calcium sulfate. As it degrades, it leads to the formation of calcium phosphate which is the main inorganic component of bone and which also serves as a stimulus for further bone regeneration. Osteoblasts attach to the calcium phosphate and deposit more bone in the defect.

Since NanoGen degrades over a controlled period as compared to traditional calcium sulfate, it provides the stimulation for bone regeneration over a much longer period. Hence robust bone regeneration is observed in defects grafted with NanoGen.

Because it is completely degradable, bone defects grafted with NanoGen are eventually completely replaced with regenerated vital bone. Research shows that availability of vital bone is important for the placement and eventual success of dental implants.



  • As a stand-alone bone graft material
  • In combination with other bone graft materials
  • To provide a resorbable barrier over other bone graft materials

How to Use

Examples of Use

Oral Surgery
Post-extraction: Carefully pack the NanoGen putty into the defect after tooth extraction. Compress the putty to ensure complete filling of the socket.The site can be closed with any of the

commercially available GTR barrier membranes (calcium sulfate, collagen, absorbable polymer or ePTFE). The alveolus should be filled to slight excess and the soft tissue margins should be approximated with sutures over the barrier membrane.

Infra-osseous defects: After periodontal treatment, fill the defect(s) with NanoGen putty, pressing on the root surface. In furcations, NanoGen can be used alone or under membranes.

Apicoectomy: Fill the crypt with NanoGen putty. After the defect is completely filled, close it with a barrier membrane.

Root perforations: Introduce NanoGen putty into the pulp chamber. Push it through the perforation into the bone lesion until the latter is completely filled. Close the perforation with fast setting super-EBA or a resin bonding technique.

Open apices: Plug the apical third of the canal with NanoGen putty, then remove the material up to 1 mm from the radiographic apex. Fill the canal with your chosen technique.

Dehiscence and fenestrations: Reconstruct the bone continuity with NanoGen putty. Close the defect with a GTR Barrier.

Mini sinus lifting: Prior to implant insertion, fill the bone area with NanoGen putty, pressing with an appropriate instrument and pushing the material so that the membrane is raised.

Great sinus lifting: NanoGen putty can be used as a single implant material for this purpose.